Madam Boss was supposedly the founder of Team Rocket (according
to the CD Drama, "The Birth of Mewtwo") and the mother of Giovanni.
Giovanni thought she was very beautiful. In the CD Drama, she refers
to Giovanni as her little "brat boy". From the single
official picture of Madam Boss, she appears to have very long, shiny
black hair. She is pictured as wearing a red and black business
suit. Like early pictures of her son, her face is shrouded in shadow.
Madam Boss was extremely obsessed with money, looking for ANY way
to make a profit. For example, when Miyamoto brings back a recording
of Mew's voice from the South American jungle, Madam Boss is first
worried about the price that her agents paid for the highly-sensitive
microphones used to make the recording. Then, Madam Boss wants to
sell the recordings to make a profit, not even thinking of the potential
to capture the rarest Pokemon of all, Mew.
Madam Boss is never heard of after the CD Drama, and 20 years after
Miyamoto left on her mission, Giovanni is in charge of the Team
Rocket organization. It is not known what happened to Madam Boss,
or when Giovanni actually took over Team Rocket.